42. Antidepressant induced homicide
In 2011, a paper was published in Pharmacogenomics and Personalized Medicine examining the relationship of antidepressants and akathisia side effects in those with genetic mutations in the metabolizing genes of the CYP450 family. In the study, eight of the subjects had committed homicide and many more became extremely violent while on antidepressants.
On today’s podcast we welcome one of the co-authors, Christopher Crotty, and subject, David Carmichael, to share their stories.
In 2011, a paper was published in Pharmacogenomics and Personalized Medicine examining the relationship of antidepressants and akathisia side effects in those with genetic mutations in the metabolizing genes of the CYP450 family. In the study, eight of the subjects had committed homicide and many more became extremely violent while on antidepressants.
On today’s podcast we welcome one of the co-authors, Christopher Crotty, and subject, David Carmichael, to share their stories.
Radically Genuine Podcast email - RadGenPodcast@gmail.com
If you are in a crisis or think you have an emergency, call your doctor or 911. If you're considering suicide, call 1-800-273-TALK to speak with a skilled trained counselor.
ADDITIONAL RESOURCES
16:00 Zhou, Y., Ingelman-Sundberg, M., & Lauschke, V. (2017). Worldwide Distribution of Cytochrome P450 Alleles: A Meta-analysis of Population-scale Sequencing Projects. Clinical Pharmacology & Therapeutics, 102(4), 688–700. https://doi.org/10.1002/cpt.690
40:00 - Carmichael, D. Calm, organized, homicidal behaviour – my connection to school shooters. Mad In America.
RADICALLY GENUINE PODCAST
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Creators and Guests
Host
Dr. Roger McFillin
Dr. Roger McFillin is a Clinical Psychologist, Board Certified in Behavioral and Cognitive Psychology. He is the founder of the Conscious Clinician Collective and Executive Director at the Center for Integrated Behavioral Health.
Host
Kel Wetherhold
Teacher | PAGE Educator of the Year | CIBH Education Consultant | PBSDigitalInnovator | KTI2016 | Apple Distinguished Educator 2017 | Radically Genuine Podcast
Guest
Christopher Crotty, PhD
Medical Writer | Health Economics and Outcomes Research (HEOR) | Market Access | Digital Health | Clinical Decision Support | CYP450 Pharmacogenetics | Healthcare Professional Training
